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Exact(6)
While basal cell carcinomas locally invade, the ability of squamous cell carcinomas to migrate and spread to other areas of the body is of great concern.
Given the observed impaired recycling of β1-integrin, its accumulation in enlarged endosomes in CEDNIK cells (Figure 6) and the distinguishable expression pattern of FAK, PAX and their phosphorylated forms in peripheral adhesions (Figure 7), we examined the ability of CEDNIK cells to migrate and spread using wound healing and cell spreading assays.
However, while this model is plausible in a limited area and over a limited period of time (for instance this is observed in areas of central Africa where hunter-gatherers still live near farmers) it is difficult to envision a simplified multigenerational scenario where only male farmers repeatedly migrate and spread their genes across Europe over several thousand years.
Infected cells have a different morphology: cells aggregate in clumps rather than migrate and spread.
These cells on the microgels were also able to migrate and spread onto their cell-conductive surrounding, which demonstrated that the cell-seeded GelMA microgels could be successfully used as injectable tissue constructs.
To evaluate whether the CSP cells adhered to the microgels could migrate and spread to other surrounding environment, a likely event after which the cells are transplanted to the target tissue, the cell-seeded microgels were placed on top of tissue-culture treated plastic surface, and monitored the cellular behavior.
Similar(54)
Among other roles, MMPs degrade the ECM and, therefore, prepare the path for tumor cells to migrate, invade and spread to distant secondary areas, where they form metastasis. Tissue inhibitors of metalloproteinases or TIMPs control MMP activities and, therefore, minimize matrix degradation.
By implanting healthy human cartilage together with RASF into severe combined immunodeficient mice, Lefèvre and colleagues demonstrated that activated RASF migrate in vivo and spread the disease to sites of implanted cartilage.
By increasing where and how much glycosylation occurs on their surface, many tumor cells develop an advantage over other cells when migrating to and spreading through other organs.
Many species of wild birds migrate and this has spread influenza across the continents throughout the ages.
In addition, PMNs could migrate and directly promote spread of mycobacteria 36.
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