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Moreover, cancer cells with suppression of CKIε expression using shRNA constructs that targeted the CKIε gene had reduced growth rates, a reduced capacity to migrate and reduced tumour growth in vivo (Fig 3).
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The second type is the electron beam irradiation, which make the material of nanopore edge migrate and reduce the nanopore diameter.
The results showed that siRNA mediated EIF5A2 knockdown in T24 and EJ cells, inhibited BC cell to migrate or invade and reduced EMT.
Mesenchymal stem cells expressing TRAIL migrate to tumours and reduce the growth of primary cancers and metastases.
Purkinje cells that failed to migrate completely exhibited conical dendrites with abnormal 3-D arborization and reduced dendritic complexity.
Comparing unreduced (-DTT) and reduced (+DTT) secretions from wild type without cement gland (WT - CG) embryos showed that the reduced samples migrate further in the gel (Fig. 7B).
This degradation has been attributed to the catalytic nature of Pt, which dissociates H2 into protons which then migrate into the PZT and reduce it at elevated temperature.
The WTb cross-linked protein apparently contained no intermolecular disulfide bonds as it migrated similarly under both nonreducing and reducing conditions.
This was achieved by treating mice with the immunosuppressive drug FTY720, which downregulates the expression of sphingosine-1-phosphate receptors (S1PRs) on the T lymphocyte surface, thereby preventing lymphocytes from migrating along a S1P gradient and reducing the T-cell egress from draining-lymph nodes (Brinkmann et al, 2010).
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The most prominent oxidised species co-migrated with fully reduced and mPEG-modified ΔS2 mutant PDI, which migrates with a distinct mobility to the reduced ΔS1 mutant (lane 8) as described earlier (Appenzeller-Herzog and Ellgaard, 2008).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com