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After grounding our argument in a discussion of stochastic noise and nongenetic heterogeneity, we explore the hypothesis that distinct chromatin domains, which are known to be dysregulated in disease and remodeled during development, might underlie cellular plasticity more generally.
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Further, they reported that complex epistatic interactions that underlie cellular functions might also be responsible for differences in network connectivity patterns as a function of a phenotypic trait.
Define the biological circuits that underlie cellular responses.
We next hypothesized that the differential response to NB-598 might underlie the dramatically different cellular responses observed in the panel of SCLC cell lines.
Disruption of MoVam7 compromised morphogenesis resulting in many small and fragmented, perhaps immature, vacuoles and endosomes, which might underlie the many other cellular function of MoVam7.
Second, increased ER stress might underlie pathological changes in cellular phenotype and function in IPF.
This further illustrates how the translocation properties of nuclear factors might underlie the kinetics of functional cellular events.
Here we review recent observations from animal models regarding the cellular and molecular basis that might underlie the addictive properties of benzodiazepines.
To try to identify cellular and molecular changes that might underlie the MB defects in p35 mutants, we extended our analysis to the ultrastructural level using electron microscopy (EM).
Functional studies show that microRNAs participate in virtually every cellular process investigated, and changes in their expression might underlie many human diseases [ 2].
To further ascertain the cellular changes occurring in GD18 LPS-exposed foetal forebrains that might underlie the defect in neuronal patterning, we examined the expression levels and distribution of GLAST, a marker for radial glia.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com