What is highlighted through this type of comparison is the substantial information loss that comes from many other approaches and how this might then affect the overall interpretation of the data.
If we consider the differences in molecular flexibility observed in H. sapiens centrins caused by their differences in calcium affinity, then it is feasible to envision the effect on the molecular flexibility of the Tetrahymena thermophila centrin (centrin 1), which might then affect formation of the centrin target complex and, in turn, the structure of the basal body within this model organism.
This might then indirectly affect the health care system; patients might not follow physicians' recommendations, ultimately leading to a vicious cycle in which all drug side-effects or all disease complications may be assumed to be medical errors.
The results indicated that, through altering the structure of neurons, REM-CSR might reduce the neuronal excitability and then affect the function of PFC.
With further deposition of collagen, the systolic motion, coronary flow reserve, and electrical activity might then be affected and contribute to pathology [ 16, 17].
Therefore, Cyr61 might regulate the activity of Rac1 through the integrin pathway and then affect the migration of PCa cells.
The statistical analyses of SNP data might then be severely affected.
However, the association of physical activity and built environment might then again be affected due to differences in the physical behaviour between residents of urban and rural neighbourhoods.
Cigarette smoke, then, might affect or even damage cell membranes, thus influencing the concentrations of related metabolites, namely the biomarkers discovered in this study.
In this example, occupation could determine income, which then might affect blood pressure by influencing whether a person can buy healthy food, receive adequate medical care, or experiences stress over financial matters.
Integration of these various lines of knowledge on bioprocesses and biospecifics in a single EGN might then suggest what evolutionary process affect what OGF (and thus what functions), in what environment.
