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A priori, pathogen-induced miRNAs might target negative regulators of the plant response to pathogen infection whereas pathogen-repressed miRNAs might target positive regulators.
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Our study suggests an alternative treatment goal to cessation of hallucinations might be to target negative outcome, reducing the duration, frequency, fear association and interference with activities of ongoing hallucinations to result in a more benign form of CBS.
Since miRNAs have been implicated in the repression of gene expression, we speculated that miR-18a might target a negative regulator of the STAT3 signalling pathway.
In this study, members of miR1520n, miR4374b, and miR4396 were up-regulated simultaneously under three stresses, which implies that they might target genes that function as negative regulators of stress tolerance.
However, these mGFP-positive endothelial cells were LacZ-negative at E18.5, suggesting that the Tbx4 lung enhancer might target endothelial progenitor cells during early lung morphogenesis.
Because mitochondria carry a negative charge [ 31], NRC-03 and NRC-07 that enter breast cancer cells might target and damage mitochondria.
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Future research might target these particular groups.
miR-21 targets negative feedback circuits in several signaling pathways.
They might negatively target the same mRNAs).
Significant interrelations between APQ dimensions suggest that different dimensions might be targeted in parallel to encourage both a more positive and a less negative perception of aging.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com