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It has become apparent that the caseum of mature granulomas might substantially impede drug penetration, limiting in vivo drug efficacy (Prideaux et al., 2011).
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Such definitions of equipoise, if literally interpreted, would substantially impede RCT-based clinical research.
Depending on the affinities and numbers of quasi-specific sites, they can substantially impede the search process due to trapping of the protein.
These included combining doctoral training and institutional responsibilities which substantially impeded research progress.
Together, the data reported in this study shows that blood-stage growth is substantially impeded, probably prevented altogether, in the absence of AMA1.
Furthermore, the unwillingness of the neonatal community to avoid giving control group infants glucocorticoids has substantially impeded the ability to obtain useful follow up information.
Further, combining KDM1 targeting drugs with current endocrine therapies substantially impeded growth and restored sensitivity of therapy-resistant breast cancer cells.
Combining KDM1 targeting drugs with current endocrine therapies substantially impeded growth and restored sensitivity of therapy-resistant breast cancer cells to treatment.
Improved triage of these samples might substantially reduce the costs.
This might substantially contribute to malaria risk in the model.
Improvement of professional performance might substantially improve clinical outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com