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IL-11 binding to IL-11Rα and glycoprotein 130 (gp130) mediates signal transduction through STAT3 activation; therefore, we next evaluated whether the CGRRAGGSC peptide might stimulate cell proliferation by activation of the same pathway.
To analyse whether PGE2 might stimulate cell proliferation in an autocrine or paracrine manner, we studied the effect of exogenously added PGE2 in cultured rat chondrocytes.
This indicates that in the bamboo growth season, environmental cues might stimulate cell division, growth or death through regulating hormone transport of influencing the expression of hormone response factors.
Other authors found that CXCL12 might stimulate cell migration, cell growth, and invasion of ovarian cancer cells (Scotton et al, 2002), and that CXCR4 was found to be expressed on the majority of glioma cell lines studied and on patients' tissue samples.
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Although the presence of MSU crystal-specific receptor at the cell surface is unlikely, MSU crystals might stimulate cells through membrane lipid alteration [ 17].
Because Wnt3 has been shown to promote the proliferation of mouse bone marrow pro-B cells [29], it was speculated that Wnt might stimulate CLL cell proliferation in an autocrine manner [9].
As CNDAC (Liu et al, 2005) and most HDAC inhibitors (Bolden et al, 2006) promote increased apoptosis through very different mechanisms, it was hypothesised that a combination of these agents might significantly stimulate cell death.
For example, transcripts required for cellular communication were highly accumulated at 36 h, suggesting that the virus might first stimulate cell-to-cell communication in fungal host cells, which is necessary to trigger host defense mechanisms against viral pathogens.
Under inflammatory conditions, eosinophils might release cytokines to stimulate cell growth and activate immune cells; they might release chemokines to attract macrophages to the bronchia to eliminate the pathogens and damaged cell debris after secretion of ECP.
TIIA treatment increased the likelihood of the occurrence of DNA damage in gastric cancer cells, which might stimulate cancer cells to increase PSMB3 expression.
DCP might stimulate HCC cell growth through the DCP-Met-JAK1-STAT3 signaling pathway.
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