The authors estimated the fraction of people that might show a response at one tenth of the dose that produces a response in 5% of exposed people.
For example, symptoms related to perseverative thinking (rumination and dwelling) and mood disturbance (chronic sad mood or anxious mood) might show more response than symptoms such as sleep and appetite disturbance.
There are three explanations for this latter finding that seem to be consistent with our evidence: First, institutions of codetermination may yield sluggish wage reactions, and longer-term estimates might show a response that mimics those without codetermination.
However, many physicians remained unconvinced of the real efficacy of the drug: They argued that the disease could relapse, even though it might show initial response[ 77, 78].
Using functional MRI, we hypothesized that vegetarians and vegans, who made their feeding choice for ethical reasons, might show brain responses to conditions of suffering involving humans or animals different from omnivores.
However, some receptors have almost no spontaneous activity but might show inhibitory responses if activated beforehand.
This raises the question of whether, if tested for longer periods of time, the humanized mice might show significant responses with tumors more consistent with those induced by a variety of non-PPARα agonists and those observed in humans (Bannasch 1996; Su and Bannasch 2003).
Although it is possible that some mutant forms might show a limited response at a lower dose and a larger response at a higher dose, our results indicate that most mutant forms that were tested at both lower and higher doses showed a "good" response at either dose.
We hypothesized that if the suppression were GABAA-mediated, a cell showing a 'loser'-like response behavior might show a 'winner'-like response behavior during blockade of GABAA-receptors via iontophoresis of BIC at the recording site (see Method section).
More sensitive pulmonary function parameters might mirror those early changes and might show a dose response.
