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Since sumoylation of HDAC1 has been shown to be important for its repressor activity, we hypothesized that SUMO-HDAC1 might show increased affinity for CoREST.
Given the role of K63 polyubiquitylation in DNA damage recognition and repair and NF-κB signaling, we reasoned that mammalian cells exposed to compound Ia might show increased sensitivities (decreased survival) to DNA damaging agents.
The risk allele associates with increased Cav-1 serum levels, and OB lesions might show increased Cav-1 expression.
Hence, we consider it being very challenging to find a time point at which the LYS1 OE line might show increased immune responses compared to wild type plants.
Specifically, one instrument might show increased HU over time while another shows a negative or no impact in the same participant.
Is it not possible that pcd mice might show increased trial-to-trial variability in their movements relative to sized-matched controls?
Similar(48)
These facts would suggest that IL-22 deficient mice might only show increased bacterial burdens at later time-points post LM infection.
Considering our study dealt with a non-clinical sample, it might be expected to show increased rGMV in the hippocampus area in science students.
If the followup period of the current study had been extended beyond the interscreen interval, these women might have continued to show increased risk of cancer beyond the due date for second screen.
However, our in vivo assessment of LDH and PDH fluxes by [1-C]pyruvate and [2-C]pyruvate, that might have been expected to show increased LDH exchange flux in the context of increased steady-state lactate, increased LDH activity, and/or increased NADH NAD+, did not confirm such an increased LDH flux (Witney et al., 2011).
If our presumed piRNA clusters were the sites of piRNA biogenesis it might be expected they should show increased levels of transcription.
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