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An x-ray might show changes in soft tissue, while US confirms fluid in that location.
Based on the fact that expression of Myc is strongly and rapidly induced by serum stimulation, and the fact that Myc is known to be an important regulator of cell proliferation, we hypothesized that Myc might show changes in binding to its target promoters in response to serum stimulation.
In human subject experiments, however, the slope might show changes over time as well.
Moreover, brains from patients with late onset of clinical symptoms might show changes occurring in usual aging in addition to those observed in HD (e.g., [ 2]).
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If LARK facilitates translation of E74A, as suggested by results shown in Figure 2, then E74A protein abundance might show diurnal changes in abundance, in phase with LARK.
Future studies might show whether changes in CP levels can be of prognostic significance for hospital stay, the need for surgery, and impact on the quality of life.
One possible explanation is that, after radiotherapy, benign tissues might show histological changes such as acinar distortion, atrophy, stromal fibrosis with granulation tissue formation, and inflammatory swelling of prostate cells, which might result in a decrease in ADC values, whereas the tumour shows an increase of ADC values.
Alternatively, an Alu element can be defined as belonging to a subfamily if it is reasonable to assume that at the moment of integration, the sequence corresponded to that of the subfamily source gene, which may have since undergone gene conversion or back mutation such that it might show diagnostic changes.
In general, experimental data might be expected to show changes in gene expression that are merely artifacts of the model system, while human tumor data alone can show patterns of correlation but do not readily demonstrate cause-and-effect in the way experimental models can.
From this viewpoint, animals exposed to 'noisy' or 'enriched' odor environments might be expected to show changes opposite to those reported here for the deprived state.
Given the close functional relationship of myosin with actin, and their joint role in cell invasion in cancer progression[22], we expected that actin might show a similar change in abundance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com