Sentence examples for might restore sensitivity from inspiring English sources
Therefore, interfering with the Stat3 oncogenic pathway might restore sensitivity to anticancer drugs.
Based on these studies we wished to determine whether atorvastatin might restore sensitivity to corticosteroids and had hoped to observe a beneficial effect of atorvastatin and inhaled beclometasone compared to inhaled beclometasone alone, but found no significant effect in outcome measures at the 8 week time point.
Moreover, considering that different resistance mechanisms may coexist in the same tumour, combination with other targeted agents with a potential for synergistic activity might be recommendable to restore sensitivity to trastuzumab.
Therefore, inhibition of the PI3K/Akt/mTOR pathway with a mTOR inhibitor such as everolimus might be a reasonable approach to overcome resistance and restore sensitivity to trastuzumab-based therapy.
Therefore, only masitinib was able to restore sensitivity to gemcitabine in Mia Paca2 cells.
Restoring TK expression only in the NPF-Gal4 circuit is not sufficient to restore sensitivity to CH503.
The L240R, H226Y, and W178S alleles do not restore sensitivity to φCr30, whereas the P263R, R161P and D194G variants partially restore sensitivity to φCr30.
Our results also showed that a GSI could partially restore sensitivity to trastuzumab in resistant tumours.
Combination therapy with EGFR and MEK inhibitors may restore sensitivity to EGFR-TKIs.
Sensitising HB cells to apoptosis may restore sensitivity of resistant HB to established therapeutic regimens.
Therefore, agents that inhibit the PI3K/Akt/mTOR pathway may restore sensitivity to trastuzumab-based therapy.
