Sentence examples for might require substantial from inspiring English sources

In a statement Tuesday, the S.E.C. said Mr. Madoff had kept multiple sets of books, so reconstructing the flow of money might require substantial effort.

Here we need to emphasize that even for small gzipped files the loading of a dataset might require substantial time proportional to the number of molecules in the dataset.

However, this might require substantial new experiments that are potentially beyond the scope of this work.

The rarefaction curve also suggests we have underestimated diversity, indicating a more reasonable estimate might require substantial sampling (up to 30 40 clones per individual).

We have employed conservative priors (uniform, Jeffreys, Gaussian) that make an analytical treatment tractable but in some cases more information could warrant a different choice of prior that might require substantial alternations to our approach to handle the numerics of marginalisation.

Compared to acorns, these multi-seeded fruits might not require substantial chewing cycles during mastication.

For instance, gaining or losing entire bony structures such as a spine or serra might require more substantial differentiation of developmental pathways (either via phenotypic plasticity or genetic divergence) than those for altering overall distal-tip shape.

More sophisticated enhancements, such as audio and video components, might require more substantial faculty development efforts, and additional research is needed on both how to better disseminate these curricula, and on practice and patient-level outcomes.

This might require a substantial amount of work that would lie outside the scope of this manuscript (for example a double knockout of both isoforms that is conditional and may not even be available), but it would certainly be helpful.

The alternative is a move towards fast reactors, which use less uranium than LWRs, however require substantial investment and development, and might never become economically viable unless uranium prices rise considerably.

Others might be on the verge of foreclosure, in homes that would require substantial investment to prepare them for sale.