Going further, he warned that ministerial control would also jeopardise the rigour scientific research, as 'a keen and energetic minister... would constantly be tempted to endeavour in various ways to secure that the conclusions reached by organised work under any scientific body... should not suggest that his administrative policy might require alteration' [ 6].
†Includes myopathy with statin treatment, or clinically relevant altered plasma concentration (for example, of digoxin, lithium, ciclosporin, or theophylline), which might require dose alteration or closer monitoring.
Significant renal impairment was defined as the combination of these two (i.e. those with eGFR less than or equal to 60 mls/min/1.73 m) as this population might require dose alteration to antiretroviral treatments.
"Without them, the gameplay changes too much, and it would require alterations to the rooms or object placement.
These store selections should come as no surprise considering many men's garments require alterations.
A number of professions require alterations to traditional sleep patterns, from doctors and police officers to bakers and garbage men.
However, one cannot completely exclude that some modifications produced by the enzymatic deficiency persist even after enzyme recovery because some alterations might require higher dose and/or longer incubation time to be reversed or could be irreversible.
Probabilities can be used in contexts from basic research to clinical applications (Lockwood et al., 2006; Pinkel and Albertson, 2005) so that a clinician might require high certainty of alteration of a specific gene before invasive procedures, whereas a basic researcher can consider for further study genes that show only a moderate probability of alteration.
Requests to step-up the level of authorization might require additional processes, agreements, or alterations to the IRB protocol (Table 22).
Therefore, formation of the bulgy shape in tadpoles may require alteration of the water permeability of the superficial epidermis of tadpole skin that might be achieved by expression of pirica (Fig. 5).
They may also require alteration.
