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These observations provide information on sortase catalysis and the semisynthetic enzymes might represent useful tools for further biochemical investigations and engineering approaches of sortases A.
These might represent useful therapeutic targets in ovarian cancer.
They suggested that MMP-2, HIF-1α and VEGF might represent useful parameters for detection of early carcinogenesis and progression of colon carcinoma.
The in vitro IFN-γ responses to these proteins might represent useful markers to evaluate changes associated with treatment of latent TB infection.
These findings suggested that TdEC and HA-EC might represent useful tools to study tumor vessel properties and, ultimately, to identify tumor vasculature markers.
However, research on these proteins is generally incomplete, and if some are in fact redox-modified, their redox-active cysteines, methionines, or other residues might represent useful therapeutic targets.
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Nonpharmacological management of GOR might represent a useful tool for neonatologists to reduce the use of antireflux medications, which should be limited to selected cases of symptomatic babies.
Because DHEA is used clinically as a long-term immuno-enhancing drug, this hormone might represent a useful therapy for preventing immunodepression in surgical patients.
To investigate whether sCD40L dosage might represent a useful tool to explore in vivo platelet function.
Our data propose Eps8 as a key molecule involved in the control of the intrinsic invasive behavior of GBM cells, and suggest that this protein might represent a useful target for the design of new drugs for the treatment of these tumors.
These findings may indicate that, also in pregnancy, the number and the content of dreams are influenced by women's mood and that the evaluation of the oneiric activity might represent a useful tool for clinicians either to investigate the women's emotional state or to predict its repercussions on the course of labour.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com