Sentence examples for might represent downstream from inspiring English sources

Profiling has also been used to identify microRNAs that might represent downstream targets of activated oncogenic pathways in primary cancers (Calin and Croce, 2006a).

Moreover, the expression profiles of clusters 3 and 12 changed obviously between the 24-h and 48-h time points, suggesting that they might represent downstream genes in the BA response pathway.

Together, these data point to a defective regulation of organelle transport in the absence of OA1 and imply that the cytoskeleton might represent a downstream effector of this receptor.

This is easy enough and while changes in DNA methylation might represent a downstream effect, the DNA methylation changes are well characterised in in suvh4 so they could still get a good idea of whether or not TrAP overexpression mimics loss of SUHV4 activity.

dunce-like optomotor phenotypes in D0264, D0067, and D0177 suggest that these mutations might compromise brain circuits relevant to dunce function (i.e., they may represent downstream plasticity genes expressed in the same cells as dunce).

The KLKs represent downstream targets by which miRNAs can affect ovarian cancer pathogenesis.

In the present study, transcriptional changes are observed at a much later stage, which might represent either the downstream effects of earlier changes in the expression of hierarchically higher genes and/or transcriptional perturbations that start at a less differentiated stage and are maintained until later stages.

In conclusion, the results of these studies demonstrate that COX-2 might represent one of the downstream targets of gastrin and that selective COX-2 inhibition is capable of reversing the trophic properties of gastrin and presumably prevent growth of CRC induced by hypergastrinaemia.

Thus, CBX2 overexpression might represent an alteration necessary to mediate the downstream epigenetic effect of PRC2 gain of function.

RSKs might represent such targets, as they are almost exclusively activated downstream of ERK1/2, controlling the proliferation and survival of a variety of cancer cell lines.

For further re-use of the treated water, the post-treatment downstream of the electro-coagulation electro-flotation systelectro-coagulation electro-flotationselectro-coagulation electro-flotation