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This pattern of expression, where Snail1 and Snail2 are co-regulated by both ligand and blocking antibody, is inconsistent with early regulation of EMT but might reflect downstream regulatory interactions.
Although neither study shows direct involvement of CLN3 in either BMP synthesis or palmitoyl-protein Δ-9 desaturation, respectively, these results might reflect downstream alterations in underlying membrane dynamics owing to the alterations in the phospholipids we report.
We also observed that GTN mediated (endothelium independent) dilatation of the brachial artery was increased after 12 months statin treatment, as has been previously reported [39,40] and which might reflect downstream statin effects e.g. on smooth muscle cell sensitivity to nitric oxide.
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This suggests that sensorimotor alpha suppression might reflect the downstream modulation of the sensorimotor cortex by mirror neuron areas in the parietal and frontal cortex (Arnstein et al., 2011; Hari et al., 1998; Nyström, Ljunghammar, Rosander & von Hofsten, 2011; Perry & Bentin, 2009).
However, these changes do not always reflect downstream in, for example, the set of target genes.
These differences may reflect downstream mechanisms differentially regulating expression of these genes in response to BRAFV600E.
The capability of the CYC and IaTCP1 genes to address a larger number of downstream targets might reflect their function in the control of monosymmetry formation, even when expressed in a heterologous species forming a polysymmetric corolla such as Arabidopsis.
These spatial differences in gene expression might be induced downstream of the ISC by region-specific signals, or they might reflect intrinsic differences in regional stem cell programming.
At this stage, the biological mechanisms underlying differential sensitivities to chronic β-stimulation are not known but might reflect distinct and strain-specific distributions of atrial and ventricular β-adrenergic receptors and/or differential downstream signalling pathways.
And my recommendation might reflect it.
This might reflect tolerance of bacterial invasion by live BEC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com