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The complexity and heterogeneity of known carcinogenesis mechanisms provides a strong rationale for combining drug interventions that might provide additive or synergistic anti-carcinogenesis effect.
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All predictors might provide an additive opportunity for early intervention and improved outcome in patients with EAC (Reid et al, 2001; Quaroni et al, 2009).
It is unfortunate that metformin plus intensive lifestyle intervention was not studied in the DPP as this combination might be expected to provide additive protection from conversion to type 2 diabetes in a prediabetic population (although no such additive benefits were observed in the IDDP; see below).
Hopefully, this could provide additive neuroprotection, contribute to tissue repair, and improve functional outcome.
The most powerful combination of NAs, ETV and TDV, could provide additive or synergistic antiviral activity.
Albuminuria and impaired GFR may provide additive prognostic information regarding health outcomes in diabetes.
While testing for single biomarkers is helpful, combined biomarker testing can provide additive prognostic information [ 30].
They might provide you with additional exercises.
Several also mentioned that toxicogenomics methods might provide insights into whether mixtures of chemicals produce additive, synergistic, or antagonistic effects.
It must be pointed out that the simulated scenarios are purely additive and other more realistic scenarios with a more complex interaction between genes and biological pathways might provide different results.
In line with this assumption, and acknowledging that GEIs might provide a resolution to the Paradox, we found that all male traits (likely to be under strong selection) harboured additive genetic variance (at least when measured at the standard thermal treatment), and that they were also all involved in G × E interactions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com