Thus, it appears that LPS-LBP induced innate immune response might not exert large impact on the association between IL-18 and the MetS prevalence.
This suggests that estrogen might not exert its effect directly on medulloblastoma cells, but rather might influence microenvironmental function.
For example, homologues of the temporal miRNAs, lin-4 and let-7 originally identified in Caenorhabditis elegans, have been found in a variety of eukaryotes, though they might not exert similar functions in different host cells[ 2].
Ted Cohen, an epidemiologist and assistant professor at Harvard Medical School, believes some drug-resistant mutations might not exert the so-called fitness costs that would otherwise compromise XDR TB bacteria and weaken them.
The phosphorylation of c-Jun in STAT1−/− explants was not expected owing to the high percentage of cell survival in our explants suggesting that c-Jun might not exert apoptotic effects in the absence of STAT1, but be involved in hair cell survival.
Because a FSCN1 inhibitor might not exert sufficient tumour-suppressive activity, and a MMP14 inhibitor might cause adverse effects, an upstream regulator of both FSCN1 and MMP14, not an inhibitor of either of them, could serve as an ideal tumour-suppressive agent.
