Sentence examples for might mediate tissue from inspiring English sources

One hypothesis proposed by other investigators is that microchimeric cells might mediate tissue repair via microchimeric stem cells.

Given the clonal variability in breast cancer cells, microarray analysis was performed on tissue-specific clonal lines to examine what genes might mediate tissue selectivity during metastasis.

Although not defined in these experiments, the most parsimonious explanation of the ability of estrogen to effect this change would be through its ability as a steroidal hormone to competitively inhibit the relatively promiscuous enzymes of steroidogenesis which might mediate tissue metabolism [ 19- 22].

P mediates acute inflammatory signaling, while Dr, S, and Type 1 may mediate tissue invasion.

In contrast to the mechanism in normal mammary tissues, ERα might mediate cancer cell proliferation via paracrine and/or autocrine modes in primary breast cancers.

However, it should be noted that when used in vivo, such metabolism-targeting drugs might mediate unwanted side effects on healthy tissues and organs that depend on the metabolic pathways targeted.

Using whole genome expression profiling in archived synovial biopsies we have established changes in key pathways and genes that might mediate both the inflammatory changes and the tissue remodelling downstream of the inflammation in SpA and AS.

Although widely expressed, they can mediate tissue-specific transcripts.

However, the observations that 1,2-saturated PAs are accumulated in the plant preferentially in reproductive and young tissues [59], [60], [61] and that these structures might mediate antifeedant activity and neurotoxic effects [62], [63] suggest an ecological role for these alkaloids.

This may be due to late treatment and advanced disease at presentation when viral or immunologically mediated tissue pathology might be irreversible.

The distinctly different but overlapping tissue distribution of the ERβ compared with the ERα suggests that it might mediate some of the non-classical effects of oestrogens and anti-oestrogens.