Sentence examples for might mediate downstream from inspiring English sources

UNC-73, UNC-33 and UNC-44 are not involved in the accumulation of UNC-40 GFP UNC-40 GFPFP torgrowth cones, suggesting that they might mediate downstream effects of UNC-50 and UNC-5 signaling, possibly on toe growth conescytosuggesting

In a previous publication [ 2], we discussed two possible mechanisms via which Rheb might mediate its downstream effects.

To assess signaling pathways that might mediate necroptosis downstream of RIPK1, we began by establishing conditions that induce necroptosis in HT22 cells using tumor necrosis factor- α (TNF α) and zVAD administration.

An RR undergoes phosphorylation, thereby modulating its ability to mediate downstream signalling.

Phosphorylation of the RR modulates its ability to mediate downstream signalling.

These phenotypic observations gave a first indication that MAPK and AKT might mediate different signaling downstream to the NGF-TrkA axis.

Genes upregulated in mab-5 e1751 gof mab-5 e1751 gofed in mand5(lof) are goodownregulatedfor those that minht mab-5 lofosterior mab-5 lofare migoodion downstream of MAB-5.

This might indicate that the expression level of SRF is not altered instead activation of the SRF might be important for mediating downstream signaling.

It is important to identify the main pathways downstream of AR transactivation that might mediate the 'androgen-independent' function of the AR.

We therefore hypothesised that RRM2, as a downstream target gene of HPVE7, might mediate HPVE7-induced HIF-1 α and VEGF expression via activation of the ERK1/2 signalling pathway.

Using whole genome expression profiling in archived synovial biopsies we have established changes in key pathways and genes that might mediate both the inflammatory changes and the tissue remodelling downstream of the inflammation in SpA and AS.