Sentence examples for might mediate cellular from inspiring English sources

O-GlcNAc modification of HSP70 might mediate cellular protection by its binding to target proteins [49].

In order to narrow down a subset of plausible genes that might mediate cellular migration and invasion, we performed unsupervised clustering analysis and selected a group of 5559 genes from a total of 48803 genes that were more than 1.5 fold significantly up- or down-regulated in at least one of the cell lines as described in the Methods (Figure 3A).

These nuclear receptors control expression of proteins that mediate cellular cholesterol release including apoE.

However, Chung et al. showed that the surface charge of mesoporous silica particles could mediate cellular uptake rate or even cellular uptake route of the particles [29].

TxA2 may also mediate cellular hypertrophy [ 68].

ROS can mediate cellular damage through direct interaction with cellular components.

Taken with the close relationship between increases in IL-8 production and cell numbers, which suggested that IL-8 secretion may directly reflect of cell number, this raised the possibility that a single, RGD-dependent mechanism might mediate the entire cellular response.

Histone levels in septic patients are significantly increased and might mediate disease aggravation by cellular injury and inflammation via TLR4 signaling, which potentially results in multiple organ failure and fatal outcome.

This suggests that nSMase1 might mediate ceramide generation, apoptosis, and other related cellular functions via JNK signaling under stress conditions in the microsomal and nuclear compartments.

The finding that the SUMO E3 ligase activity is required for the ability of PIAS1 to antagonize EMT suggested that specific SUMO substrates might mediate the effect of PIAS1 on this fundamental cellular process.

Autophagy also functions as a mechanism of pro-cell death, depending on the cellular context that when unrestrained can result in progressive consumption of cellular components and subsequent cell death and might mediate resistance to anticancer therapies such as radiation, chemotherapy, and some targeted therapies.