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From that perspective, a supra-physiological concentration of miR-155 minducenduce adverse effects through alteration of "low affinity" targets.
From a clinical viewpoint, chemotherapy of NB might induce adverse effects concerning tumor biology.
Vaccination of GALT3 peptide for patients with brain tumour might induce adverse events because of its expression in normal brain and the other normal tissues.
It was hypothesized that repeated BMP-7 injections into the knee joint might induce adverse effects such as synovial fibrosis, ectopic cartilage and bone formation, or osteophyte formation.
However, an effective dose of 1,25(OH 2D3 might induce adverse effects such as hypercalcemia, because mice receiving over 0.1 μg of 1,25(OH)2D3 every other day for 2 weeks had hypercalcemia of over 12 mg/dL [ 50].
In laboratory animals exposed to TCDD, adverse effects (hormonal, reproductive, and developmental) have been observed at body burdens in the range of 28 73 ng TCDD/kg body weight (van Leeuwen et al. 2000), hence suggesting that DLC exposure in this fish-eating population might induce adverse health effects.
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The full length Aβ as antigen might induce meningoencepholontis adverse effect since the middle and C-terminal fragments of Aβ contain T cell epitopes.
Given that rFVIIa has demonstrated a good safety profile in other studies, this observation may suggest that high doses in patients without severe bleeding might induce some adverse events in either future trials and/or clinical use.
Interestingly, the greater sensitivity of proliferating Caco-2 to Cr VI) relative to differentiated Caco-2 predicts that Cr VI) exposure in vivo might induce more adverse effects in crypt enterocytes than villous enterocytes.
Lead contents at all sites, was higher than ERL, ERM, PEL and ISQG guidelines, suggesting that Pb in sediments from the Birim River might be periodically expected to induce adverse biological effects on the biota.
Metabolism of levomepromazine and haloperidol is catalyzed by CYP2D6 and if given to the patient with lack activity of this enzyme might have induced adverse effects even on standard doses [ 3].
Related(20)
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