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On the other hand, expression changes in HR-/ERBB2 tumors might indicate downstream activation of the pathway occurring despite the negativity of ERBB2.
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With respect to the downstream effects of PERK-ATF4 activation, this might indicate that we have to look for another protective ER stress factor to explain the cardioprotective role of metformin.
Thus, the exon1 to exon2 region might indicate the location of the 2DL5-2DS35 gene block (centromere or telomere) while the downstream region (intron3 to exon9) might be predictive of linkage association (2DS3 or 2DS5).
However, our findings might indicate the relative failure of national regulations or national ethics committees to have a downstream effect on the practices of the research staff.
This might indicate that the expression level of SRF is not altered instead activation of the SRF might be important for mediating downstream signaling.
"His mellow reaction might indicate sympathy".
His record as governor might indicate otherwise.
This might indicate introgression.
This might indicate that the variation in R FR ratio at the canopy level in densely grown plants was sufficient to change phytochrome photoequilibrium and to trigger downstream expression changes.
This might indicate that either MK-2206 is not as specific as described or that RT4 cells possess phosphorylation levels that are non-detectable by western blotting but are sufficient to regulate further downstream signalling events.
This might indicate an awareness/recognition problem.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com