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While most memory research has focused on developing drugs that might improve memory – so-called cognitive enhancers – the thought that if one drug improved memory, another that blocked the effect of the first might impair it attracted a number of small start-up biotech companies interested in cashing on the potential PTSD market.
Some researchers have speculated that they, too, might improve memory.
We anticipated that in the event middle condition, cues at midpoints of the video might improve memory for midpoint information in older adults, but that it would impair memory for event boundary information.
Assuming that upregulation of GABAA receptor-mediated inhibition, which usually occurs with aging, was accelerated in APP/PS1 mice, we next examined whether a treatment aimed at normalizing inhibition might improve memory in adult APP/PS1 mice.
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Since we observed enhanced inhibition in adult APP/PS1 mice, we hypothesized that PTX treatment might also improve memory in this mouse model of AD. Adult APP/PS1 and adult nonTg mice were given daily injections of PTX (1.0 mg/kg in a volume of 10.0 ml/kg) or saline vehicle intraperitoreally in their home cages for 10 days.
It was up to her. "Mom," I explained, "when we went to the doctor for your physical, he told you there was a pill you could take that might improve your memory, and you were very enthusiastic about taking it".
Our results suggest that fasting or activation of CRTC might be able to improve memory deficits, by inducing fLTM formation.
The findings, published in the April issue of Nature Neuroscience, might lead to new drugs to improve memory function in amnesia and neurodegenerative diseases.
We hypothesized that cuing at event boundaries would improve memory, and that this might reduce age differences in memory.
Moreover, there has been intense interest in the potential of flavonoids to modulate neuronal function and to improve memory [ 22], as well as their activation of microglia and astrocytes that might shape synaptic plasticity [ 27].
But the herb did not improve memory in healthy people.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com