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We determined whether these novel CAD risk variants are associated with carotid atheroma, assessed by CIMT, and other intermediate risk markers which might implicate causative pathways, in a large panel of extended families that has been shown to have adequate power to detect small genetic influences on quantitative traits, including CIMT [6].
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We investigated association of reported CAD risk variants with CIMT, and with other intermediate phenotypes that may implicate causative pathways.
Unfortunately, our genome scan included both males and females of each species; therefore, we cannot use divergent loci to implicate causative genes at the sex-determining locus.
Boras dismissed the idea that Canseco might implicate Rodriguez.
The results might implicate that different angiogenic pathways exist in human breast cancer.
This might implicate these genes in chemoresistance.
Bacterial ocular floras are the implicated causative agents.
Many of the other features such as premature loss or greying of the hair and osteoporosis are more commonly seen with aging, suggesting that premature tissue aging might be implicated as a causative factor [8].
Inhibitory mechanisms might be implicated but might differ, depending on whether it is anticipatory or postinitiation.
A right-to-left shunt (RLS) might be implicated in the pathogenesis of this disorder [3].
Inflammatory injury and induction of oxidative stress have been implicated as causative factors in neurodegenerative diseases such as Alzheimer's disease (AD).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com