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One hurdle that might impair stable neo-cartilage formation is the issue of chondrogenic hypertrophy, which has been identified in studies on MSC-mediated chondrogenesis using several bone morphogenetic proteins (BMPs) in vitro and in vivo [ 1, 8, 11- 13].
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It is thought that the mutant molecule is stable but might impair Endostatin-induced angiogenesis inhibition by mechanisms that are still not clear [ 17].
More gloomy news arrived late Friday when the credit rating agency Standard & Poor's affirmed its investment grade credit rating on the company's bonds but lowered its outlook from stable to negative, warning that the AOL division's poor results might impair its ability to pay down its debts.
Reflection, it has been said, might impair our "moral clarity".
"But I worry that controversy around the memorial might impair it as an instrument of healing".
That might impair the lucrative socialism these capitalists enjoy.
Calpers also took Mr. Prince to task for business relationships that might "impair" his objectivity as a board member.
His manner with patients was acceptable, although consultants also noted "a willingness to please that might impair judgment".
An improbable change might impair performance in change detection (Beck, Angelone, & Levin, 2004).
Likewise, it had been suggested that vasopressin might impair hepato-splanchnic blood flow [34].
First, crushing tablets before administration via the gastric line might impair their effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com