Exact(4)
The NPP1 pathway might hence represent a potential therapeutic target to treat insulin resistance in human metabolic disease.
Additionally, K8 was released as a circulating marker from apoptotic non-small cell lung carcinoma cells as a full-length and proteolytic cleavage-resistant protein and might hence represent a valuable biomarker for head and neck malignancies [ 34].
In addition, we demonstrate that blockade of the PDCD1/CD274 pathway leads to increased tumour cell clearance in the TCL1tg mouse model and might hence represent a promising new option in treatment of this disease.
This strongly suggests that the neuronal function of UNC-51 is independent of the interaction with EPG-1 and the latter might hence represent an autophagy-specific interaction partner, just as VAB-8 and UNC-14 are for axon guidance and axon outgrowth.
Similar(56)
The differences previously observed might, hence, not only represent the presence of a specific trisomy but also interindividual variations and comparisons between non-identical cell types, with the latter introducing severe interpretation difficulties.
This might further impact viability of endothelial cells, angiogenesis and adhesion function and hence might represent a possible target for future therapeutic strategies [ 33].
Unlike any of the peptidergic neurons characterized here, the dorsal ap-let neurons seem to have extensive arborizations within the neuropil of each hemineuromere [91] which appear to contain no or only little peptide immunoreactive material [92], [93] and hence might represent dendritic regions.
Indeed, a similar but small number of unique chromosomal rearrangements were identified in each genome (131 in genomic, 78 in cell line; see Additional files 3, 4. 5); 34% and 45% of these unique junctions, respectively, had been detected in more than 75% of all other genomes sequenced by CGI at that time and hence might represent false positives (Additional files 4 and 5).
To determine whether these uORFs have characteristics similar to canonical genes, and hence might indeed represent transcribed protein-coding regions, we compared their A+T content, amino acid composition, and start and stop codon usage (supplementary tables S1 S3, Supplementary Material online).
And it is not hard to imagine circumstances under which, a decade or two hence, he might represent the future of the country as well.
Hence, slanDC might represent a good candidate for the APC that engulfs CD47low leukemia cells.
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