One place the protein shows up prominently in those with Parkinson's is in the gastrointestinal tract, where scientists have hypothesized it might first misfold and form clumps, then travel on the vagus nerve to the brain.
Nevertheless, studies resorting to isotopic determination of extracellular volume have hypothesized that CSW might be more prevalent in the setting of neurosurgical ICU than is SIADH [216, 217].
We have hypothesized that p73 might have a role in Noxa induction and apoptosis.
Armed with these findings Chung et al. have hypothesized that LanCL1 might have an activity analogous to bacterial LanC, wherein LanCL1 is involved in formation thioether linkages using GSH as one substrate.
As TRPS1 has a GATA domain, many researchers have hypothesized that it might play some roles in tumorigenesis in human tissues.
Nevertheless, studies resorting to isotopic determination of extracellular volume have hypothesized that CSW might be more prevalent in the setting of neurosurgical ICU than is SIADH [ 216, 217].
However, based on the presence of a basic surface patch having electrostatic surface potential similar to eIF4-E, Bitto et al. (2005) have hypothesized that BLES03 might be involved in nucleic acid binding.
Several models have hypothesized how oligomers might disrupt cellular membranes, including transmembrane oligomeric pore structures reminiscent of those of pore-forming toxins [ 30, 45], nonspecific binding of amyloid oligomers to the membrane surface [ 44, 46], and detergent-like membrane dissolution by amyloid fibrils growing on the membrane surface [ 47].
Investigators elsewhere have hypothesized that these chemicals might increase risk of obesity and metabolic diseases.
"One of the things that we have hypothesized is that some of the deteriorating conditions of these cities is what might have driven these murder rates," she said, citing economic factors like unemployment and alcohol consumption.
