Sentence examples for might function downstream from inspiring English sources

Interestingly, knockdown of STAT5 impaired IL-2 induced Shc mediated stimulation of Akt activation through the IL-2 receptor[14] suggesting that Gab2 might function downstream of STAT5.

We, therefore, next examined whether ERK might function downstream of BLT2 to mediate paclitaxel resistance in MCF-7/DOX cells.

These TFs might function downstream of key cell cycle TFs to regulate the transcription of a specific group of genes.

Moreover, WRKY2 was down-regulated in spl, suggesting that it might function downstream of SPL in anther development.

Therefore, we next examined whether PI3K and ERK might function downstream of PAFR in CDDP-treated ovarian cancer cells.

Because Baz/Par-3 is recruited to adherens junctions (Le Borgne et al., 2002), we speculated that Baz might function downstream of E-cadherin to anchor the centrosomes.

12 Our data, for the first time, demonstrated that in chondrocytes, β-catenin might partially function downstream of activated Rac1 in modulating pathological changes in chondrocytes.

Duan, R. et al. Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo.

This demonstrated that the AP2 genes function downstream of miR172.

CG16772 may also function downstream of tra [ 41].

Further, considering the possible function of gene orthologs, we finally chose 26 genes for RNAi analysis, and to find more genes promoting regeneration, we increased the dsRNA feeding times to 4. Finally, we found that only Dis3l2 RNAi) and Mrpl21 RNAi) animals exhibited regeneration defects, suggesting that these two genes might function as Fir1 downstream genes (Fig. 4F).