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In addition, it is also reasonable to propose that decreasing the overall DNA methylation might facilitate cell fate conversion by reducing the methylation levels on the genes specifying for other cell fates.
The staining was weak in cells with normal morphology but became stronger in the cells with condensed nuclei, suggesting that the interaction might facilitate cell death.
We postulated that p85β might facilitate cell invasion.
Similarly, digestion of the basement membrane and extracellular matrix proteins might facilitate cell migration and invasion [ 27].
Activation of other signaling pathways when IM blocks the BCR-ABL-mediated pathway might facilitate cell death avoidance in CML [ 51].
These data supported that SOCS3 methylation-associated inactivation might facilitate cell motility, and SOCS3 reactivation by 5-aza-2'-deoxycytidine treatment inhibited migration of A549 cells.
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These results provide the first indication of how highly regulated and dynamic Notch-based intercellular communication might facilitate cell-cell communication and the propagation and synchronisation of the well-established intracellular clock gene oscillations.
The superior hydrophilicity of the PLGA/nHA/CM scaffolds might easily facilitate cell migration into the pores following blood immersion in vivo.
Compensatory mechanisms mediated by other inhibitory receptors might facilitate NK cell education in these CD94-deficient mice [31], [32].
These findings suggest that CCN3, through its interaction with S100A4, might alter cytoskeletal organization and facilitate cell motility.
In summary, overexpression of PRL-3 might facilitate tumour cells to invade into lymphatics or vasculature, and therefore being a prerequisite for development of local lymph node and distant metastases.
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