Third, other causal genes, which are implicated in the pathogenesis of cancer, might mask the effect of SHMT1 C1420T polymorphisms by gene gene interactions and, consequently, modulate cancer susceptibility.
Thus, stress signals affect the viscoelastic properties of nucleoli and consequently modulate their functions.
We therefore examined the possibility that Pin1 may also regulate ΔNp63α protein level and consequently modulate its activity, by a similar mechanism.
In this pathway, Wnts activate β-catenin signalling and consequently modulate the expression of specific target genes that regulate cell proliferation, apoptosis, and cell fate [ 1, 2].
Many proteins are targeted for covalent modification by SUMO, which consequently modulates many cellular processes [2] [4].
Thus, DNA methylation must be modulating chromatin regions and, consequently, modulating the mRNA transcription of immune-inflammatory genes related with periodontitis, impacting the prognosis of disease.
Editing alters the amino acid sequence in these substrates, consequently modulating receptor functional properties and activity levels.
In conclusion, our results indicate that IFN-α regulates the activity of the MEK/ERK pathway and consequently modulates cellular proliferation through a Ras / Raf -independent mechanism.
It is possible that by forming a complex with E-cadherin and/or β-catenin, CA125/MUC16 could re-distribute EGFR and consequently modulates its signalling pathway.
Deaths from undetected pathogens that cause gastroenteritis might consequently be attributed to gastroenteritis of unknown etiology.
