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Reasonably, our pipeline might cause false negative detection as well.
By using this approach we lower the chance that unknown confounders might cause false positives.
To follow patients longitudinally, it was essential to prevent minor wrist or hand rotation from session to session which might cause false variations in volume measurements.
Thus, misinterpretation of strains as active bla CTX-M producers based on false positive PCR amplification might cause false reporting of bla CTX-M genes in K. oxytoca.
The first option would lead to a loss of non-orthologous sequences, and simultaneously might cause false positive results by mismatch-hybridization.
Therefore, eliminating factors which might cause false positives (i.e., contamination introduced through reagents, laboratory disposables or equipment including carry-over contamination between tests or sample-to-sample contamination, etc).
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In the latter case, an arbitrarily taken sample might cause false-negative results.
But selection of high value for might causes false matching of edges whereas very low threshold might cause missing of true moving edges in the final detection result.
The lack of many representative outgroups might causes false positives, i.e. some proteins might be inaccurately included in our list.
Although, non-CG methylation is observed in the ES cells and chromosome Y has some homologies to the chromosome X, two things that might cause a false estimation of the calculation, the false positive rate of these two methylomes is considerably low.
2. Noise might cause a false move, but the chance is extremely small.
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