Exact(6)
I'm asking him to swim a river, though it might be upstream".
Mitochondrial dysfunction might be upstream of axon degeneration in aSyn-expressing cells.
This control experiment provides evidence that the inhibition of mitochondrial respiration by AKTIV might be upstream of its effects on the PI3K/Akt pathway.
Overall, we conclude that At-FLA4 regulates normal root growth via an ABA-depedent signalling pathway that might be upstream of cell wall biosynthesis.
These results suggest that WNT2B and miR-185-3p miR-185-3p miR-185-3pulators of vimightn and E-cadherin and induce the genesis of the EMT phenotype.
To test the hypothesis that TCL1A might be upstream of cytokine expression, we knocked down TCL1A using the same four siRNAs used to perform the experiments shown in Figure 2A, with or without the addition of 0.1 nM E2, and then assayed both TCL1A and IL-17RA mRNA expression by quantitative RT-PCR.
Similar(53)
Y1H screens by Mitsuda et al. (2010) have identified nine proteins capable of binding the promoter region of RD29A, whereas non-Y1H studies by Tsutsui et al. (2009) further suggest that a DREB-family protein, CEJ1/DEAR1, might also be upstream of RD29A.
The activity of DGAT1 was proposed to be regulated by post-translational modification (Yu et al. 2002) and PKA might be the upstream regulator (Haagsman et al. 1981 , 1982 Rodriguez et al. 1992).
Studies in rodent [41] [43] and goat [44] oocytes suggest that MPF might be an upstream regulator of the MAPK/Mos pathway during meiotic maturation.
One possibility is that DCL2 might be required upstream of dsRNA production to recognize the substrates and/or recruit RDR6, after which DCL2 and other DCL enzymes produce siRNAs from the resultant dsRNA.
In the present study, we found that the expression of ath5 was significantly reduced in the retinas of Atoh8 knock-down zebrafish, suggesting that Atoh8 might be the upstream regulator of ath5 in the retina.
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Justyna Jupowicz-Kozak
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