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So the world might be heterogeneous by, for instance, instantiating-here red and instantiating-there green.
The first question concerns whether there is reason to believe that the effects estimated using IVs might be heterogeneous, that is, differ among the groups of respondents.
The variety of drugs reported to be effective in HH (see below) also underscores the possibility that the pathophysiology might be heterogeneous.
So the world might be heterogeneous by, for instance, instantiating red here and green there.[53] The third way to allow for heterogeneity without contradiction is to regionalize instantiation.
When working with experimental results that come from multiple sources the data might be heterogeneous: In one case the binding affinity might be measured by (K_{i}), in another case by (K_{d}) and in a third case by (IC_{50}).
There are two major complications to this procedure: At any given region of the genome a tumour might be heterogeneous for a DNA copy number change, such that a proportion of the tumour cells show a change and the remainder are normal or show a different DNA copy number change.
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[A review of summary measures is given in Liu [ 20].] Using an average over any of these measures might be problematic: not only might sensitivities and specificities be heterogeneous, this might also be true for the associated summary measures such as the Youden index or the Euclidean distance (as demonstrated by Figure 2 using the data of the meta-analysis of BNP and heart failure).
Hence, many of the putatively homogeneous blocks (contributing to Figures 4A and 5A) might prove to be heterogeneous if there were greater depth of coverage resulting in more reads spanning multiple SNPs.Figure 6 plots the density of heterogeneous blocks for CEU_TRIO across the genome.
The second problem is that the people recruited by DNA Sciences might be too heterogeneous.
The most possibly underlying reason might be the heterogeneous biological properties of UCB.
Thus, each of the four groups might be somewhat heterogeneous due to differing motivations for preferred mode of delivery.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com