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Some researchers suggested that the key might be gene expression, the rate at which messenger RNA and proteins are made from a gene, but the evidence has been scant.

Another important source of LSGs might be gene duplication.

Prime candidates for consideration might be gene variants responsible for foetal bone development, and/or environmental exposures such as nutritional factors or infections.

Therefore, the chromatin status might be gene or cell type-specific and the level of histone acetylation might not necessarily reflect the level of gene expression.

One possibility is that there might be gene expression changes occurring in MTLn3 cells cells within the tumor microenvironment that provide an advantage in entering the circulation but impair the ability to extravasate or seed lung metastases.

Such discrepancies suggest that the function of histone methylation might be gene specific and depend upon the recruitment of different trans-acting complexes, or that methylation status might be dynamic and titrated during gene expression by the concerted activity of histone methyltransferases (HMTs) and demethylases (HDMs) [ 20- 23].

Similar(53)

Other possible targets might be genes whose expressions are regulated by this signature.

This suggested that there might be genes encoding AHL acylases in the genome of strain JG1.

In principle, one could imagine that there might be genes regulated by the cell cycle, which might have strong or weak oscillations, and in addition there might be other genes that do not oscillate.

The enriched immune-related contigs might be genes that assist carp in resisting pathogens or might be of help in adapting to different aquaculture growing environment.

For example, in mammals there might be genes responsible for rapid calcification of bones that lead to late-life calcification of atherosclerotic plaques (an example suggested by Williams).

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