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The agents might be cells.
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However, the results might be cell line dependent as found using 1.9-nm GNPs (AuroVistTM) and two different cell lines, DU-145 and MDA-MB-231 cells.
Thus, the effects of the AKT pathway in regulating FASN levels might be cell type specific.
We next posited that H2BK37me2 might be cell-cycle regulated, and therefore synchronized wild-type cells in G2/M with nocodazole and harvested cells at defined points along the cell cycle following nocodazole release.
The differences observed in our HEK 293 cell-based study compared to the MCF7 cell-based study by Sedgley et al. [26] suggests that nuclear localization might be cell type-dependent.
This effect might be cell line- specific.
This specificity, however, might be cell type-specific.
This difference in results might be cell-type specific.
However, the effects of senescent cells on angiogenesis might be cell-type dependent.
Therefore, p53-dependent resistance of tumour cells might be cell type-dependent.
We also considered that γ-H2AX expression or etoposide function might be cell-cycle dependent.
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