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The first indication that a cancer's protective shield might be breached came in 2010, after a trial of the drug ipilimumab in patients with otherwise untreatable melanoma.
Then, fearing that levees might be breached, water managers sought to prevent even more disastrous flooding by opening Barker's spillway gates, inundating already sodden neighborhoods downstream.
Friend-of-the-court briefs filed by the Times, by the company that owns this magazine, and by other news organizations testify to the fear that a protection they have long taken for granted might be breached.
Foreign ownership has increased so much that on March 21, Telus was required to issue a news release stating that its restrictions on foreign ownership — no more than 33.3 percent — might be breached.
It was a drama that reached a conclusion late last week, when the State Department, responding to fears that its security might be breached by a secretly placed device or hidden software, agreed to keep personal computers made by Lenovo of China off its networks that handle classified government messages and documents.
Mr Rahman told the court he was advised by the council's chief legal officer that his human rights might be breached if he answered questions in council meetings about his "responsibilities".
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The Twin Cities were not threatened by the weather, but the presidential candidate John McCain felt it was insensitive to begin the convention as a hurricane was bearing down on New Orleans, with misplaced fears that its defences might again be breached.
Third, the Europa defences might also be breached, but a defender holding the narrow Europa Pass or the heights of Windmill Hill could easily enfilade an invader; as Jones put it, "two hundred men on Windmill Hill and Europa Pass ought to hold as many thousands at bay".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com