Sentence examples for might affect mitochondrial from inspiring English sources

However, the D-loop variations located within the central block (CB) and conserved sequence block 2 (MT-CSB2) might affect mitochondrial biogenesis, since they are located outside the two hypervariable regions.

Downregulation of metabolic genes suggested that MeCP2 might affect mitochondrial function.

NAA is synthesized mostly in mitochondria (17), and our data indicate that insulin might affect mitochondrial processes in neurons.

These observations suggest that decreased pfcrt expression, regardless of its haplotype in the 7G8 background, might affect mitochondrial integrity and functions.

We propose that upregulation of DIRK1A and/or DSCR1 in DS might affect mitochondrial gene expression, and thereafter mitochondrial function, through the calcineurin/NFAT pathway.

Increased ROS production in neurodegenerative process might affect mitochondrial parameters and also ATP production, membrane potential, permeability transition pore (MPTP) activation, and calcium uptake.

Conversely, proteasome inhibition might in turn affect mitochondrial respiration.

The present study thus clearly demonstrates that, also at subcytotoxic concentration, HEMA, TEGDMA, and BDDMA might affect the mitochondrial activity by inducing alterations in energy metabolism, oxidative stress, and GSH balance in HPCs.

How do both features in AD relate to each other and might the two molecules synergistically affect mitochondrial integrity?

The induction of apoptosis could be a consequence of the cytotoxic activity of MI-D, as it is already known that drugs, which affect mitochondrial metabolism, might facilitate the induction of cell death and overcome apoptosis resistance in cancer cells (Susin et al, 1998; Colombo et al, 2001).

It is interesting that respiration loss did not globally affect mitochondrial membrane potential, which might be due to reversal of ATP synthase (Fig 3A).