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Furthermore, these data suggest that KRIT1 might affect cell adhesion processes via integrin signaling in CCM1 pathogenesis.
Detachment of cells using trypsin is not recommended as it might affect cell surface proteins which this method aims to isolate.
These five proteins might affect cell polarity through intracellular trafficking.
Although the capacity of GSH to abrogate the activity of NSMase is well established, GSH could have other effects on bacterial sonicates that might affect cell apoptosis.
The reduction of maximum stress of the F-actin-FLNa network by these two mutations, therefore, might affect cell survival under large mechanical stress.
These findings suggest that Pkd1 or/and Kif3a deficiency might affect cell fate decision between osteoblastogenesis and adipogenesis through regulation of hedgehog signaling pathway.
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A drug might affect cells that are normal as well as cells that need to be fixed, causing side effects.
TLR4 signaling in the MG thymic milieu might affect cell-to-cell interactions, favoring autoreactive T-cell activation.
The exact biologic effects of synovial IL-20 have yet to be determined, but it is tempting to speculate that this cytokine might affect cells present in inflamed synovium.
Although it was apparent that DOX was cytotoxic to Y-79 cells, the sustained growth-inhibitory effects observed by the cell viability assay indicate that DOX might also affect cell proliferation.
Since CBM complex contributes to cell proliferation and survival by regulating growth factor-induced NF-κB pathway (Jiang et al., 2011; Pan et al., 2016), we hypothesized that CBM complex might also affect cell death induced by DNA damage response.
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