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The participants--including epidemiologists, physicians, and experimental biologists--had an animated discussion about miscarriage, lactation, and other issues relating to pregnancy, and how they might affect breast tissue and a woman's likelihood of developing cancer.
Potentially, many risk factors linked to SEB might affect breast cancer outcome.
There are several mechanisms by which glucocorticoid prescriptions might affect breast cancer risk in subpopulations defined by molecular subcharacteristics.
Breast development and hormonal changes at puberty might affect breast cancer risk, but epidemiological analyses have focussed largely on age at menarche and not at other pubertal stages.
Thus, there are biologically plausible models and correlative human clinical studies suggesting that insulin acting through insulin receptors might affect breast cancer risk and progression.
To gain insight into mechanisms by which chemokines might affect breast cancer development through local and microenviromental migration signalling, we analysed malignant and normal tissue samples from patients with breast cancer regarding their chemokine expression profiles.
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Furthermore, genes deleted in the 11q13 amplification event might also affect breast cancer outcome and treatment response.
However, we postulated that SML might differentially affect breast cancer outcomes based on ER status, as suggested by the distinct distribution of SML between ER+ and ER− breast tumors (Fig. 1a).
We speculate that coffee might contain compounds that differentially affect breast cancer of different ER subtypes.
Coffee itself might contain compounds that differentially affect breast cancer of different ER subtypes.
Comorbid diseases can affect breast cancer prognosis.
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