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For example, in S. coelicolor, along with the mature antibiotic(s), intermediates of the biosynthetic pathway might activate expression of the export genes, thereby coupling resistance to biosynthesis Hopwood 2007.
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Furthermore, they also suggest that Hedgehog signaling might activate the expression of cited3 via activating the expression of myod and myf5 (Lewis et al., 1999; Osborn et al., 2011) in the adaxial cells.
RAG-1 and RAG-2 might activate the expression of the V(D J recombinase but, more likely, they directly participate in the recombination reaction.
Various mechanisms were proposed to explain how the deletion might activate their expression in FSHD muscles (reviewed in [12]; [12]).
As the prfA gene was also not detected in these isolates, we suggest that a secondary promoter might activate the expression of hly and plcA and originate the observed phenotype.
While Viotti et al. have shown that a gap-junction-dependent Ca2+ signal can travel from the node to the left LPM, they stop short of providing a mechanism by which Ca2+ might activate Nodal expression in the LPM.
It is thus possible that Ttk69 is a mechanistic link between Notch and its responsive genes in FCMs: Notch signaling might activate Ttk69 expression in FCMs as discussed below.
The most obvious source of a sequence that might be able to activate expression of the rightward genes in our new piggyBac vectors was the downstream 3'-TRD, which includes the piggyBac 3' terminal repeat and a 172 bp internal domain sequence with an 83% AT content [ 4, 18].
Such changes might be explained by localized, specific and direct effects of a TTC5/EP300 complex at gene promoters to repress or activate expression respectively.
In addition, we found that EIF5A2 might activate TGF- β1 expression to induce EMT and drive aggressiveness in BC cells.
Although the molecular mechanism behind plant treatment with OLIGOs is not fully understood, it is clear from this report that they might activate homologous gene expression and this event is accompanied by gene demethylation.
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