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Therefore, we propose that SXR activation might activate a different panel of gene in liver or colon tissue in comparison to breast tissue which may explain its different role between tissues.
The Toll, Imd (immuno deficiency), JNK (jun-kinase) and the JAK/STAT (janus kinase/signal transducers and activators of transcription) pathways are all characterized by extracellular signal recognition by membrane bound receptors, which might activate a signalling cascade resulting ultimately in the transcriptional activation of effector molecules in the nucleus.
"Remember Jewish history in Europe: chemical gas is more than a redline for us," says a customer.Some analysts argue that Israel is better off with the devil it knows, than with a jihadist resurgence, which might activate a front that the Assads have kept quiet since 1973.
Or one might activate a mechanism by placing it in the precipitating conditions for the phenomenon and observe how the entity or activity changes as the mechanism works.
From reading the literature, he knew that Szechuan pepper might activate a particular group of nerve fibers, known as RA1 fibers, which respond to light touch and vibration.
If not for all the reasons listed above, maybe for this added bonus: A 2013 study found that when people who smoke regularly work out, exercise might activate a "second hit" effect, increasing THC levels in the bloodstream for a short period of time.
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Therefore, we are further investigating the possibility that in addition to the STING-IRF3 pathway, cGAMP might activate an unknown signaling pathway that involves the adapter molecule MyD88.
When the authors performed comparative gene expression profiling of normal and LMO2 expressing thymocytes, they noted upregulation of several HSC specific genes and suggested that ectopic expression of Lmo2 might activate an HSC specific transcription program.
It could be expected that presynaptic ASIC1a during the 6-s-long local acidification used in this work might activate during a few hundreds of milliseconds to then be inactivated.
We hypothesized that GM-CSF might activate monocytes in a way that modulates their function during intestinal inflammation.
The AH-3 ΔwaaE had an ability to induce PO activity in crayfish at a low level but could not activate melanization in T. molitor larvae or it might activate melanization to a very low extent which could not be observed.
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