Sentence examples for might act downstream from inspiring English sources
Genetic data suggest that CED-3, CED-4 and CRT-1 act in the same pathway to promote early events in regeneration and that CED-3 might act downstream of CRT-1, but upstream of the conserved DLK-1 kinase implicated in regeneration across species.
The data suggest that Dmrt2b might act downstream of Hedgehog gene transcription.
To explore what might act downstream of PKG in thermotolerance, we looked for potential candidate molecules known to be intermediaries of both PKG and K+ channels.
Since ADNP is lost from pericentromeric heterochromatin in these cells (see Figure 2), we reasoned that ADNP might act downstream of Suv39 and H3K9me3 in maintenance pathways of constitutive heterochromatin.
To test whether the MRN complex is indeed involved in SHM and the possibility that it might act downstream of UNG, we analyzed the in vivo SHM patterns in the Ig locus in cells from ATLD (Mre11 deficient) and NBS (NBS1 deficient) patients.
This raises the important question of what other transcription factors might act downstream of Gata3.
We have found that this compound acts independently of the PI3K and AKT enzymes and might either act downstream of these molecules or act via other pathways.
This epistatic relationship between mad and dTIEG suggests that dTIEG might act either downstream of or in parallel to Mad.
Src kinase might act directly downstream of GPCRs and FZD receptors via its interaction with ADAMs and MMPs [ 62- 65].
Some asymmetries, such as the right-sided bias of PKCγ-dependent phosphorylation of the proteoglycan syndecan-2, occur temporally between the earliest steps in the LR asymmetry pathway (ion flux and serotonin) and asymmetric gene expression (Kramer et al., 2002), and therefore might act as downstream mediators in the serotonin pathway.
A prediction of this hypothesis is that differentiation signals would act downstream of noise elevation and might even be important for noise reduction once cells enter an irreversible differentiated state.
