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The combination of type I lissencephaly and midline calcification is reportedly pathognomonic of MDS [1].
Head ultrasound had shown dilated bilateral ventricles and head computed tomography type I lissencephaly with midline calcification (Fig. 1).
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The intracranial calcifications along the midline that we observe in zebrafish embryos have, so far, not been reported in individuals with ENPP1 mutations; however, an individual suffering from hypophosphatasia due to a KLOTHO mutation has been diagnosed with calcifications along the midline of the brain (Ichikawa et al., 2007).
Note displacement of periurethral calcifications (thick arrows) from midline.
There was no evidence of midline bow-formed ligament sclerosis and since calcification and stenosis of other arteries were present, the celiac trunk stenosis was attributed to arteriosclerosis.
"Eggshell calcification.
"A midline fin.
"But you say it crosses the midline?" "She says it crosses the midline," I said.
"You cannot look at calcification in isolation.
The research will measure their rates of coronary artery calcification.
"I believe they might indeed notice the calcification," he said.
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