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At minimum three (slow, medium, and fast dissolving) dosage forms should be designed, where the extreme ones are used to build a model able to predict in vivo bioperformance of the "middle" formulation.
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The obtained BEPs are compared with those obtained if the middle surface formulation is used.
Furthermore, the second-order mean drift force based on the middle-field formulation can be calculated analytically by using the coefficients of the Fourier Laguerre expansion.
The case study begins with the formulation of the middle range theory (MRT), based on existing theory and past actor experience.
On the other hand, IgG1 and to a lesser extent IgG2 were the dominant subtype in Montanide ISA-51 formulation [Fig. 2b, middle panel].
For CONST1 and CONST2 optimization, only two formulations were used and a middle one (with medium dissolution rate) was predicted.
Using their proximity to the center of power and media amplification, the rich, masquerading as the middle class, have a disproportionate influence in policy formulation and the Indian government's allocation of funds.
This had the effect of undermining the whole basis on which his theory had been erected, and at the same time rendered impossible the very formulation of a "law of excluded middle" for such statements.
Andrx may have the best shot at winning the court battle because it claims to have developed a patented two-layer formulation that completely avoids Astra's middle layer.
The obtained results are in close agreement with the theoretical formulations concerning ionospheric storm effects at middle latitudes.
The middle plane in-plane displacements are included in the formulation and the common axisymmetry restriction is not imposed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com