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It remains unclear whether such a reduction of colony forming units may be sufficient in the per se nonsterile middle ear compartment to prevent severe infections or biofilm forming, other than in situations when sterile work is required like in bone and joint operations [ 51].
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The functions of the biological barriers in the skin (external ear canal), mucosa (middle ear cavity), and inner ear compartments were measured using Gd-MRI at various time points.
Biofilm growth in per se nonsterile compartments like the middle ear cavity has to be expected.
Second, in a chinchilla model for AOM, Johnson and colleagues found that abrogation of protein D's activity reduced NTHi adherence in the middle ear, but not in the nasopharynx suggesting a compartment-specific effect [ 26].
After transtympanic injections of silver nanoparticles (AgNPs), the signal intensities in the perilymphatic compartments significantly increased while extremely intense signal was also detected in the external ear canal skin, middle ear mucosa, indicating the enhanced uptake of Gd-DOTA associated with AgNP administration (L in Fig. 2a, b) (Table 1).
He then developed middle ear problems.
There is no middle ear cavity and no external ear.
It is the middle ear, not the inner ear.
Persistent effusions of the middle ear.
Tympanometry is used in evaluating middle ear functional conditions.
Prosthesis dislocations and extrusions are common in middle ear surgery.
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