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Within the middle client-binding domain of Hsp90α, residue His demonstrated the most rapid adduction with kobs of 1.08 ± 0.17 h–1 in HNE-treated cells.
The Hsp90 middle client-binding domain thus may play a signicant role in HNE-mediated disruption of Hsp90 client protein interactions.
If there is a hierarchy of terms, it should have consumer at the bottom, customer in the middle and client at the top.
"I recently sold a Georgian estate in Berkshire to a Middle Eastern client who wanted to live near the queen".
In the middle of client meetings, I would sneak a peek at my phone to see whether I had received any communications.
A deduced amino acid sequence possessed three structural domains: N-terminus (1 211) ATP binding domain, middle (281 540) client protein interacting domain and C-terminus (541 698) dimerization domain; the N-terminus and middle domain is linked by a charged linker domain (212 280).
Mr. Atabeyki broke into naval design a decade ago when a Middle Eastern client retained him to design what is known today as the M147, a 147-meter megayacht that was to be built at the Blohm & Voss shipyard in Hamburg, at an estimated price exceeding A's $300 million.
Take luxury e-commerce company Moda Operandi, which recently made its biggest sale to date -- a one-of-a-kind, $413,000 ruby necklace -- to a Middle Eastern client in its London showroom.
Additionally, having done work for a large Fortune 500 corporation may not impress your middle market client if you are showcasing a line of services they have zero interest in.
How much do your Middle Eastern clients differ from your Western ones?
Middle Eastern clients are a significant market for many brands showing in Paris or Milan.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com