In Equations 4 and 5, BSA denotes the body surface area, and t i in Equation 5 indicates the mid-time of the last frame of the [18F]fluciclatide scan (60.5 min).
WNLLS minimizes the weighted residual sum of squares (WRSS) WRSS p = ∑ i = 1 n w i C t i, p MODEL − C T t i 2 (2)with p, t i, and n indicating respectively the parameter vector [K1 k 2 ;Vb], the mid-time of the i th frame, and the number of frames.
Time points for group C patients were: baseline (mid-time of ECMO course) and 4 h and 10 h after baseline.
These time points were chosen to roughly correspond to the course in group S patients, who received their surfactant approximately at the mid-time of the ECMO course.
Wong et al. [ 93] describe a technique in which they create three sequential images (each 15 min duration) starting 10 min after FDG injection combined with three arterialized venous samples taken at the mid-time of each scan.
Chest radiographs for group S were obtained before surfactant application (baseline), 24 and 48 h thereafter, and for group C at baseline (mid-time of the ECMO course), and 24 and 48 h thereafter.
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where C i is noise-free simulated radioactivity concentration at frame number i, Rand is a random number from a Gaussian distribution with a mean 0 and variance 1, ϵ is a scaling factor that determines the noise level, Δt i is scan duration of frame number i, t i is mid-scan time of frame number i, and λ is 11C decay constant.
Germination curves were fitted using the four-parameter logistic function of SigmaPlot v.9 software to calculate the mid-time point of the germination curve (T1/2).
In a one-year period, 5,213 new and recurrent episodes of infectious conjunctivitis were registered in a mid-time population of N = 375,899.
We used the mid-time population of the participating practices as the epidemiological denominator.
