The CLIF-SOFA is relevant for discriminating both in-ICU and mid-term mortality in critically ill cirrhotic patients.
We observe a good predictive value of MELD score measured at baseline (ICU admission), even in the context of multi-organ failures, to predict mid-term mortality.
The appearance of functional mitral valve insufficiency in the setting of ischemic or dilated cardiomyopathy is an indicator of bad prognosis, with increased early and mid-term mortality and morbidity and with a significant decrease in life expectancy.
Cystatin C was a stronger predictor of renal dysfunction and mid-term mortality than serum creatinine.
The relation between BMI and mid-term mortality was non-linear and risks were higher in the extremes of BMI (P<0.001).
Adjustment for smoking, BMI, and diabetes reduced but did not eliminate the effects of social deprivation on mid-term mortality (1.017, 1.007 to 1.026, P<0.001).
Multivariable analysis identified social deprivation as an independent predictor of mid-term mortality (hazard ratio 1.024, 95% confidence interval 1.015 to 1.033 P<0.0011.033 P<0.001
With regard to reperfusion therapies, they have been shown to be effective in reducing short and mid-term mortality in patients with ST-segment elevation AMI [ 3- 8].
The major finding of our study is that DM patients undergoing TAVR seem to have favorable outcomes with similar short and mid-term mortality rates compared with non-DM patients.
However, mid-term mortality and rate of rehospitalization after TAVI are considerably high in specific patient cohorts, suggesting that selection criteria for the identification of patients who would benefit most from TAVI procedures need to be refined.
In this model, diabetes carried a 31% increased risk and smoking a 29% increased risk of death (table 3, fig 2). Figure 3 shows the non-linear effects of varying BMI on the risk of mid-term mortality, where lower and higher BMI both carry increased risk, with approximate 95% confidence intervals.
