Sentence examples for microvascular pressure from inspiring English sources

Our objective was to test the hypothesis that the ultrasound pulsing interval (PI), microbubble injection site and microvascular pressure significantly influence the transport of 100-nm microspheres to muscle through extravasation sites created by the destruction of microbubbles with ultrasound.

One can understand the potential interest in limiting pulmonary microvascular pressure during the period that endothelial permeability is increased.

At the end of 1 h, microvascular pressure was determined by double-occlusion technique and partition of total pulmonary vascular resistance (RT) was calculated.

However, the magnitude of microvascular pressure changes during lung inflation is modest and insufficient to explain the occurrence of severe pulmonary edema during mechanical ventilation with a high tidal volume.

In early publications, the development of pulmonary edema during mechanical ventilation was ascribed to increased lung microvascular pressure, resulting from high lung volume ventilation and surfactant depletion [6, 7, 16].

Schematically, two principal mechanisms can work toward an increase in pulmonary water and possibly alveolar flooding: on the one hand, an increase in pulmonary microvascular pressure and on the other hand, an increase in alveolocapillary barrier permeability.

As a matter of fact, Parker et al. showed that mean lung microvascular pressure increased by 12.5 cm H2O during ventilation of open-chest dogs at 64 cm H2O positive inspiratory pressure [16].

The increase in transmural microvascular pressure, even if modest, contributes to the severity of pulmonary edema, which may be fulminating during VILI, because any increase in the driving force will have a dramatic effect on edema formation in the face of an altered microvascular permeability [27].

Larger animals, such as dogs, withstand much higher microvascular pressures without losing the structural integrity of the capillary network [ 14].

The microvascular pressures differ from one tumor to another depending upon the vascular architecture, viscous resistance offered to blood flow and interstial fluid diffusion [ 37- 39].

In elegant experiments undertaken in the laboratories of West and colleagues [ 12- 15], electron microscopy was used to demonstrate the potential for mechanical disruption of the microvasculature – 'capillary stress fracture' – to occur when microvascular pressures are elevated to very high levels relative to their usual operating conditions.